BRHNY-Series Bio-Burden Reduction Grade Nylon Plus+ filter cartridges feature Nylon 6,6 membrane with an advanced positively-charged surface modification that is highly efficient in capturing submicronic particulate matter much finer than the stated mechanical rating. This offers a well-proven capability for highly efficient retention of haze, colloids, and color bodies. Specific to its use in medical applications, pyrogenic endotoxins are effectively removed as is well-documented in field use, industry journals, and laboratory data. Superior microbial retention is achieved to deliver a stable and consistent effluent. Moreover, the BRHNY+ series offers a more cost-effective alternative to hollow-fiber cartridges in many high-purity applications.

Cartridges are manufactured in a cleanroom environment and are flushed with 18 megaohm ultra-high purity water to ensure cleanliness, low extractables, and quick rinse-up for service use. Tolerant of repeated hot water sanitization and in-situ steam sterilization cycles for maximum service life. Each element is diffusion tested to Global Filter standards of integrity in order to assure consistent and optimal performance.

Endotoxin Removal

Bacterial endotoxin is the pyrogen of greatest concern in the pharmaceutical and medical
device industries. BRHNY+ filter elements have demonstrated capability to remove bacterial endotoxin to below a 0.005 EU/milliliter detection limit at all data points in independent testing.

Typical Applications

• Medical device reprocessing
• Water for Injection (WFI)
• Endotoxin removal
• Pyrogen removal